An Optimal Control Approach to Cancer Treatment under Immunological Activity
نویسندگان
چکیده
Mathematical models for cancer treatment that include immunological activity are considered as an optimal control problem with an objective that is motivated by a separatrix of the uncontrolled system. For various growth models on the cancer cells the existence and optimality of singular controls is investigated. For a Gompertzian growth function the optimal synthesis is described.
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تاریخ انتشار 2009